NYDDB
Well-Known Member
Jadotha, thank you for posting this- I had seen it before, but not read it all the way through. This risk factor was new to me-----
Geriatric Cognitive Impairment
Neutered male dogs and spayed female dogs are at increased risk of progressing from mild to severe
geriatric cognitive impairment compared to intact male dogs55. There weren’t enough intact geriatric
females available for the study to determine their risk.
Geriatric cognitive impairment includes disorientation in the house or outdoors, changes in social
interactions with human family members, loss of house training, and changes in the sleep-wake cycle55.
The investigators state “This finding is in line with current research on the neuro-protective roles of
testosterone and estrogen at the cellular level and the role of estrogen in preventing Alzheimer’s disease in
human females. One would predict that estrogens would have a similar protective role in the sexually intact
female dogs; unfortunately too few sexually intact female dogs were available for inclusion in the present
study to test the hypothesisâ€55
Geriatric Cognitive Impairment
Neutered male dogs and spayed female dogs are at increased risk of progressing from mild to severe
geriatric cognitive impairment compared to intact male dogs55. There weren’t enough intact geriatric
females available for the study to determine their risk.
Geriatric cognitive impairment includes disorientation in the house or outdoors, changes in social
interactions with human family members, loss of house training, and changes in the sleep-wake cycle55.
The investigators state “This finding is in line with current research on the neuro-protective roles of
testosterone and estrogen at the cellular level and the role of estrogen in preventing Alzheimer’s disease in
human females. One would predict that estrogens would have a similar protective role in the sexually intact
female dogs; unfortunately too few sexually intact female dogs were available for inclusion in the present
study to test the hypothesisâ€55