Here goes...We've tried:
Thunder Shirts and Comfort wraps
Quiet Moments (a combination of melatonin, L-theanin, chamomile and passion flower)
Lavender in bedding and as a collar
Trazadone
Trazadone with Quiet Moments
Zylkene
Zylkene with Quiet Moments
Diffuser (Angus pee'd on it)
Buffered baby aspirin with Quiet Moments
Composure Pro -previously for fire works.
All of these did little if anything to help with the anxiety and the Trazadone made it worse as the dose wore off. I forgot to mention we did discuss acupuncture with the vets and none of them thought it would help.
She also has a new behavior of being very hesitant to cross "lines". As in transitions from carpet to hard wood, patio to grass. She is even going so far as to walk around rugs and hesitate at the door thresholds. Not sure if this is from the supplements we've been trying or part of the anxiety. Reminds me of Alzheimer type behaviors that some people get.
As far as timing of doses we've done both AM and PM - no discernible difference.
Behaviors are worse first thing in the morning and late afternoon, or if someone comes to the door, excited play inside the house by other dogs. Her being able to calm down takes between 30 to 90 minutes of panting, pacing. then laying down and yawning, licking nose/lips, then paws, staring off into space and then finally going to sleep. If any of this happens too soon after eating we have vomiting added in there during the panting phase. We are getting walks in, weather permitting, and she is so excited on the walk we almost always have vomiting before we get back.
I'm taking a look at what she is eating also. We do feed raw so maybe she isn't getting the balance she needs. Our 4 proteins right now are chicken, beef, elk and venison. I picked up a bag of Merrick Salmon recipe to see if adding some healthy fats into her diet might help.
Any and all suggestion welcome!