I was home (working from home) with Jack most of the time when he was 2-5 months old. Then I used to take him to daily care every morning (from 6 months old). Then I left him home (with an open crate) and nothing bad happened. As long as I "forget" a bedroom door open, he'll cuddle in the bed and sleep most of the day (I have video surveillance, so I can see him). If I don't leave the door open, he'll fuss around more but he still won't chew anything.With the girls, well there's a totally different story. They have access to laundry room (it's a big one, and they have their crates and food and water there) and also to an enclosed part of the back yard. They chill outside in the shadow most of the time, and they become distressed if locked inside and chew me out of home. Being two of them, they don't have any kind of separation anxiety. Odd enough, they don't sleep in the same place: each of them goes to her favorite place (opposite directions), but they still play together from time to time. So, my advice, see what works for your puppy, get feedback from neighbors (if the puppy is loud when you're not home) and buy lots of toys and stuff so it won't get bored quickly.